Lapatinib

Datasheet MSDS
Catalog Number
SEGF10165
Product Name
Lapatinib
CAS Number
231277-92-2
Synonyms
GW572016, GSK572016
Molecular Formula
C29H26ClFN4O4S
Molecular Weight
581.06
Purity
99.89%
Solubility
DMSO: 93 mg/mL (160.1 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Lapatinib (GSK572016, GW2016), used in the form of Lapatinib Ditosylate, is a potent EGFR and ErbB2 inhibitor with IC50s of 10.2 and 9.8 nM, respectively, in cell-free trials. Lapatinib induces ferroptosis and autophagy.
Target
C-Raf-1, c-Src, EGFR, HER2/ErbB2
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