Catalog Number
SIKB26314
Product Name
TRAM34
CAS Number
289905-88-0
Synonyms
TRAM 34 , TRAM-34 , Triarylmethane-34 , Triarylmethane-34 , TRAM-34 TRAM 34
Molecular Formula
C22H17ClN2
Molecular Weight
344.84
Purity
99.76%
Solubility
DMSO: 3.5 mg/mL (10 mM)), with gentle warming ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
TRAM-34(Kd=20 nM), an effective and specific inhibitor of the intermediate-conductance Ca2+-activated K+ channel (IKCa1, KCa3.1), does not block cytochrome P450. The selective activity of TRAM-34 is 200 to 1500-fold than other ion channels.
Target
IKCa1 (KCa3.1)
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