Ro 90-7501

Datasheet MSDS
Catalog Number
SATM14125
Product Name
Ro 90-7501
CAS Number
293762-45-5
Molecular Formula
C20H16N6
Molecular Weight
340.38
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Ro 90-7501 is an amyloid β42 fibril assembly inhibitor (EC50: 2 μM). Ro 90-7501 inhibits ATM phosphorylation and DNA repair. Ro 90-7501 also inhibits PP5 in a TPR-dependent manner. RO 90-7501 selectively enhances TLR3 and RLR ligand-induced IFN-β gene expression and antiviral response.
Target
Amyloid β42, ATM, Protein phosphatase 5, Apoptosis
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