ZM 447439

Datasheet MSDS
Catalog Number
SSRC10691
Product Name
ZM 447439
CAS Number
331771-20-1
Molecular Formula
C29H31N5O4
Molecular Weight
513.59
Purity
99.11%
Solubility
DMSO: 51.4 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
ZM 447439 is a selective and ATP-competitive inhibitor for Aurora A and Aurora B with IC50 of 110 nM and 130 nM, respectively. It is more than 8-fold selective for Aurora A/B than MEK1, Src, Lck and has little effect against CDK1/2/4, Plk1, Chk1, etc.
Target
Aurora A, Aurora B, Lck, MEK1, Src
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