Catalog Number
SAUR11824
Product Name
SC514
CAS Number
354812-17-2
Synonyms
SC 514 , SC-514 , GK 01140
Molecular Formula
C9H8N2OS2
Molecular Weight
224.3
Purity
100.00%
Solubility
DMSO: 22.4 mg/mL (100 mM) Ethanol: 2.2 mg/mL (10 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
SC-514 is a selective, orally active, ATP-competitive IKK-2 inhibitor (IC50=11.2±4.7 μM), obstructs NF-κB-dependent gene expression.
Target
Aurora B, CDK2/CyclinA, IKK2, p38α, PRAK
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