Pemetrexed disodium hydrate

Datasheet MSDS
Catalog Number
SDHF12146
Product Name
Pemetrexed disodium hydrate
CAS Number
357166-30-4
Synonyms
Pemetrexed disodium hemipenta hydrate , Pemetrexed sodium hydrate , LY-231514 Disodium Hydrate , Pemetrexed sodium hydrate , Pemetrexed disodium hemipenta hydrate LY-231514 Disodium Hydrate
Molecular Formula
C20H21N5O6·5/2H2O·2Na
Molecular Weight
516.42
Purity
99.16%
Solubility
DMSO: 10mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Pemetrexed Disodium Hydrate is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 65 nM, respectively.
Target
DHFR, GARFT, Thymidylate synthase
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