PHA680632

Datasheet MSDS
Catalog Number
SFGF10378
Product Name
PHA680632
CAS Number
398493-79-3
Synonyms
PHA-680632, PHA 680632
Molecular Formula
C28H35N7O2
Molecular Weight
501.62
Purity
99.03%
Solubility
DMSO: 93 mg/mL (185.4 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
PHA-680632 is a potent inhibitor of AuroraA, AuroraB, and AuroraC, with IC50 of 27nM, 135nM, and Chemicalbook120nM, respectively, 10 to 200 times higher than the IC50 values acting on FGFR1, FLT3, LCK, PLK1, STLK2, and VEGFR2/3.
Target
Aurora A, Aurora B, Aurora C, FGFR1, PLK1
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