Cafestol

Datasheet MSDS
Catalog Number
SCOX17467
Product Name
Cafestol
CAS Number
469-83-0
Molecular Formula
C20H28O3
Molecular Weight
316.43
Purity
99.84%
Solubility
DMSO: 5 mg/mL (15.8 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
CAFESTOL is a ERK inhibitor for AP-1-targeted activity against PGE2 production and the mRNA expression of cyclooxygenase (COX)-2 in LPS-activated RAW264.7 cells. Cafestol has strong inhibitory activity on PGE2 production by suppressing the NF-kB activation pathway.
Target
ERK, COX-2, NF-κB
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