Ruscogenin

Datasheet MSDS
Catalog Number
ANC00083
Product Name
Ruscogenin
Structure
Ruscogenin
CAS Number
472-11-7
IUPAC Name
(1S,2S,4S,5'R,6R,7S,8R,9S,12S,13R,14R,16R)-5',7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icos-18-ene-6,2'-oxane]-14,16-diol
Synonyms
FlebopoM; HeModren; Rectolander; Ruscogenin, froM Ophiopogon japonicus; (1B,3B,25R)-SPIROST-5-ENE-1,3-DIOL; RUSCOGENIN; RUSCOGENINE; (25R)-spirost-5-ene-1-beta,3-beta-diol
Molecular Formula
C27H42O4
Molecular Weight
430.6
Appearance
White powder
Purity
>98%
Density
1.18g/cm3
Melting Point
198-202°C
Boiling Point
563.1±50.0°C (Predicted)
Description
Ruscogenin is an important steroid saponin extracted from Ophiopogon japonicum. It alleviates blood-brain barrier dysfunction induced by cerebral ischemia by inhibiting TXNIP/NLRP3 inflammatory body activation and MAPK pathway, and has significant anti-inflammatory and antithrombotic activities.
SMILES
C[C@@H]1CC[C@@]2([C@H]([C@H]3[C@@H](O2)C[C@@H]4[C@@]3(CC[C@H]5[C@H]4CC=C6[C@@]5([C@@H](C[C@@H](C6)O)O)C)C)C)OC1
InChI
InChI=1S/C27H42O4/c1-15-7-10-27(30-14-15)16(2)24-22(31-27)13-21-19-6-5-17-11-18(28)12-23(29)26(17,4)20(19)8-9-25(21,24)3/h5,15-16,18-24,28-29H,6-14H2,1-4H3/t15-,16+,18-,19-,20+,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI Key
QMQIQBOGXYYATH-IDABPMKMSA-N
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