Chrysin

Datasheet MSDS
Catalog Number
ANC01959
Product Name
Chrysin
Structure
Chrysin
CAS Number
480-40-0
IUPAC Name
5,7-dihydroxy-2-phenylchromen-4-one
Synonyms
57Dihydroxyflavone; NP005901; NP005901; NP-005901; Galanginflavanone.5,7-Dihydroxyflavone; Chrysine; 5,7-Dihydroxy-2-phenyl-4H-chromen-4-one; Crysin
Molecular Formula
C15H10O4
Molecular Weight
254.241
Appearance
Light Yellow Solid
Purity
≥98%
Melting Point
286-289°C
Description
Chrysin is a natural flavonoid with antioxidant, anti-inflammatory, and anticancer properties. It blocks COX-2 gene expression, PGE2 production, and hydroxyl radical formation in LPS-induced RAW 264.7 cells. Chrysin inhibits insulin-induced HIF-1α expression (~50% at 10 μM) in human prostate cancer DU145 cells and blocks DU145 xenograft-induced angiogenesis in vivo. In a mouse model of ischemia/reperfusion injury, chrysin decreased pro-inflammatory gene expression and oxidative stress, resulting in a reduction of infarct volume and neurological defects.
SMILES
C1=CC=C(C=C1)C2=CC(=O)C3=C(C=C(C=C3O2)O)O
InChI
InChI=1S/C15H10O4/c16-10-6-11(17)15-12(18)8-13(19-14(15)7-10)9-4-2-1-3-5-9/h1-8,16-17H
InChI Key
RTIXKCRFFJGDFG-UHFFFAOYSA-N
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