Baicalein

Datasheet MSDS
Catalog Number
ANC01989
Product Name
Baicalein
Structure
Baicalein
CAS Number
491-67-8
IUPAC Name
5,6,7-trihydroxy-2-phenylchromen-4-one
Synonyms
5,6,7-trihydroxy-2-phenylchromen-4-one
Molecular Formula
C15H10O5
Molecular Weight
270.24
Appearance
Yellow Powder
Purity
>98%
Density
1.548g/cm3
Description
Baicalein (491-67-8) is an inhibitor of protein tyrosine kinase in leukemia (CEM) cells. Induces cell cycle arrest and apoptosis.1?Originally reported as a selective inhibitor of 12-lipoxygenase, baicalein has since been shown to inhibit both 12-LO and 15-LO (IC50=0.64 μM for 12-LO and 1.6 μM for 15-LO).2 Baicalein displays anti-inflammatory activity and inhibits adjuvant-induced arthritis. Also inhibits prolyl oligopeptidase (IC50=36 μM).3
SMILES
C1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C=C(C(=C3O)O)O
InChI
InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChI Key
FXNFHKRTJBSTCS-UHFFFAOYSA-N
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