PRIMA-1Met

Datasheet MSDS
Catalog Number
SP5311163
Product Name
PRIMA-1Met
CAS Number
5291-32-7
Synonyms
APR-246 , APR-246
Molecular Formula
C10H17NO3
Molecular Weight
199.25
Purity
99.57%
Solubility
DMSO: 20mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
PRIMA-1MET restores wild-type conformation and function to mutant p53, and triggers apoptosis in tumor cells. PRIMA-1MET also targets the selenoprotein thioredoxin reductase 1 (TrxR1), a key regulator of cellular redox balance.
Target
p53 activator, TrxR1 inhibitor
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