Catalog Number
SFLT10482
Product Name
A-443654
CAS Number
552325-16-3
Molecular Formula
C24H23N5O
Molecular Weight
397.47
Solubility
DMSO: 100 mg/mL (251.59 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
A-443654 is a specific Akt inhibitor with a Ki value of 160 pM that interferes with the mitosis process and bipolar spindle formation
Target
Akt1, Akt2, Akt3, PKA, RSK2, PKCγ, CDK2, PKCδ, GSK3β, ERK2, cKIT, Chk1, CK2, SRC, KDR, MAPK-AP2, Flt1
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