A674563

Datasheet MSDS
Catalog Number
SCDK11967
Product Name
A674563
CAS Number
552325-73-2
Synonyms
A 674563 , A-674563 , A-674563 A 674563
Molecular Formula
C22H22N4O
Molecular Weight
358.44
Purity
98.0%
Solubility
DMSO: 67 mg/mL (186.9 mM) Ethanol: 15 mg/mL (41.8 mM) Water: 66 mg/mL (184.1 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
A-674563 is an Akt1 inhibitor with Ki of 11 nM, modest potent to PKA and >30-fold selective for Akt1 over PKC.
Target
Akt1, CDK2, ERK2, GSK-3β, PKA
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