Catalog Number
SGSK27067
Product Name
LY2090314
CAS Number
603288-22-8
Molecular Formula
C28H25FN6O3
Molecular Weight
512.53
Purity
99.88%
Solubility
DMSO: 93 mg/mL (181.5 mM) Ethanol: 2 mg/mL (3.9 mM), warmed ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
LY2090314, an effective GSK-3α/β inhibitor (IC50: 1.5 nM/0.9 nM), may improve the efficacy of platinum-based chemotherapy regimens. LY2090314 has been used in trials studying the treatment of Leukemia, Advanced Cancer, and Pancreatic Cancer.
Target
GSK-3α, GSK-3β
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