Selumetinib

Datasheet MSDS
Catalog Number
SERK19053
Product Name
Selumetinib
CAS Number
606143-52-6
Synonyms
ARRY-142886 , AZD6244 , AZD6244 ARRY-142886
Molecular Formula
C17H15BrClFN4O3
Molecular Weight
457.68
Purity
99.00%
Solubility
DMSO: 84 mg/mL (183.5 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Selumetinib (AZD6244) is an effective, specific inhibitor of MEK1 and ERK1/2 phosphorylation (IC50: 14/10 nM).
Target
MEK1
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