Tozasertib

Datasheet MSDS
Catalog Number
SAUR11814
Product Name
Tozasertib
CAS Number
639089-54-6
Synonyms
VX 680 , MK-0457
Molecular Formula
C23H28N8OS
Molecular Weight
464.59
Purity
99.96%
Solubility
DMSO: 46.5 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
MK-0457 is a pan-Aurora kinase inhibitor (Kis: 0.6/18/4.6 nM for Aurora A/Aurora B/Aurora C). It shows selectivity against more than 190 different kinases.
Target
Aurora A, Aurora B, Aurora C, Bcr-Abl, FLT3
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