Nilotinib

Datasheet MSDS
Catalog Number
SBCR10062
Product Name
Nilotinib
CAS Number
641571-10-0
Synonyms
AMN107, Tasigna
Molecular Formula
C28H22F3N7O
Molecular Weight
529.52
Purity
99.83%
Solubility
DMSO: 26 mg/mL (49.1 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Nilotinib (AMN-107) is a specific BCR-ABL inhibitor with IC50 below 30 nM in mouse bone marrow progenitor cells. Nilotinib (AMN-107) induces autophagy by activating AMPK.
Target
Bcr-Abl
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