Catalog Number
SEGF10206
Product Name
Brivanib
CAS Number
649735-46-6
Synonyms
BMS-540215, BMS-540215
Molecular Formula
C19H19FN4O3
Molecular Weight
370.38
Purity
98.0%
Solubility
DMSO: 69 mg/mL (186.3 mM) Ethanol: 3 mg/mL (8.09 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Brivanib (BMS-540215) is an ATP competitive VEGFR2 inhibitor with an IC50 of 25 nM, moderate inhibition of VEGFR-1 and FGFR-1, but more than 240 times more effective than acting on PDGFR-β. Phase 3。
Target
EGFR, FGFR1, Flk1, VEGFR1, VEGFR2
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