Relamorelin

Datasheet MSDS
Catalog Number
RP0075
Product Name
Relamorelin
Structure
Relamorelin
CAS Number
661472-41-9
Synonyms
BIM28131; BIM 28131; BIM-28131; BIM-28163; BIM 28163; BIM28163; RM131; RM-131; RM 131; Relamorelin;N-((R)-3-(benzo[b]thiophen-3-yl)-1-(((R)-1-(((S)-1-((4-carbamoylpiperidin-4-yl)amino)-1-oxo-3-phenylpropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-1-oxopropan-2-yl)piperidine-3-carboxamide
Molecular Formula
C43H50N8O5S
Molecular Weight
790.98
Appearance
Solid powder
Purity
98%
Density
1.36±0.1 g/cm3 | Condition: Temp: 20°C Press: 760 Torr
Solubility
Soluble in DMSO, not in water
Boiling Point
1216.2±65.0°C | Condition: Press: 760 Torr
Storage
-20°C Freezer
Description
Relamorelin is a synthetic, centrally penetrant, selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR). It is potentially useful for the treatment of diabetic gastroparesis, chronic idiopathic constipation, and anorexia nervosa. It is a pentapeptide and an analogue of ghrelin. It produces increases in plasma growth hormone, prolactin, and cortisol levels, and increases appetite in humans. It is under development by Rhythm Pharmaceuticals and is in phase II clinical trials.
SMILES
C1CC(CNC1)C(=O)NC(CC2=CSC3=CC=CC=C32)C(=O)NC(CC4=CNC5=CC=CC=C54)C(=O)NC(CC6=CC=CC=C6)C(=O)NC7(CCNCC7)C(=O)N
InChI
InChI=1S/C43H50N8O5S/c44-42(56)43(16-19-45-20-17-43)51-41(55)34(21-27-9-2-1-3-10-27)49-39(53)35(22-29-25-47-33-14-6-4-12-31(29)33)50-40(54)36(48-38(52)28-11-8-18-46-24-28)23-30-26-57-37-15-7-5-13-32(30)37/h1-7,9-10,12-15,25-26,28,34-36,45-47H,8,11,16-24H2
InChI Key
IPMQOGDSJZQLFX-BIBZJUPHSA-N
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