Mizagliflozin

Catalog Number
A16083
Product Name
Mizagliflozin
Structure
Mizagliflozin
CAS Number
666843-10-3
Synonyms
DSP-3235 free base , KGA-3235 free base , GSK-1614235 free base
Molecular Formula
C28H44N4O8
Molecular Weight
564.67
Purity
98.66%
Solubility
Methanol: 250 mg/mL (442.74 mM), Need ultrasonic DMSO: 100 mg/mL (177.09 mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Mizagliflozin is a sodium-glucose transporter inhibitor( Ki of 27 nM for human SGLT1). Mizagliflozin displays 303-fold selectivity over SGLT2. Mizagliflozin is used as an antidiabetic drug that can modify postprandial blood glucose excursion. Mizagliflozin also exhibits potential in the amelioration of chronic constipation.
Target
hSGLT1 hSGLT2
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