Catalog Number
SCAS20769
Product Name
(E/Z)-GO289
CAS Number
694522-87-7
Molecular Formula
C17H15BrN4O2S
Molecular Weight
419.3
Purity
99.68%
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2. (E/Z)-GO289 exhibited cell type-dependent inhibition of cancer cell growth that correlated with cellular clock function. The discovery of (E/Z)-GO289 provides a direct link between the circadian clock and cancer regulation and reveals unique design principles underlying kinase selectivity.
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