Tetrahydrocoptisine

Datasheet MSDS
Catalog Number
SERK19088
Product Name
Tetrahydrocoptisine
CAS Number
7461-02-1
Synonyms
STYLOPINE , STYLOPINE
Molecular Formula
C19H17NO4
Molecular Weight
323.34
Purity
98.00%
Solubility
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble DMSO: Soluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
1. Tetrahydrocoptisine has effective effects in suppressing inflammation. 2. Tetrahydrocoptisine possesses a protective effect on LPS-induced ALI through inhibiting of NF-κB signaling pathways, which may involve the inhibition of pulmonary inflammatory process. 3. Tetrahydrocoptisine has gastroprotective activity, is attributed to reducing NO production and adjusting the pro-inflammatory cytokine, inhibited neutrophil accumulation and NF-κB expression. 4. Tetrahydrocoptisine is an active anti-inflammatory constituent by inhibition of TNF-α, IL-6 and NO production possibly via down-regulation of NF-κB activation, phospho-ERK1/2 and phospho-p38MAPK signal pathways.
Inquiry

new products