GNF2

Datasheet MSDS
Catalog Number
SBCR10072
Product Name
GNF2
CAS Number
778270-11-4
Synonyms
GNF 2, GNF-2
Molecular Formula
C18H13F3N4O2
Molecular Weight
374.32
Purity
99.08%
Solubility
DMSO: 37.4 mg/mL (100 mM) Ethanol: 18.7 mg/mL (50 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
GNF-2 is a highly selective, allosteric, non-ATP competitive Bcr-Abl inhibitor. GNF-2 inhibits Ba/F3.p210 proliferation with an IC50 of 138 nM.
Target
Bcr-Abl (K562 cell line), Bcr-Abl (SUP-B15 cell line)
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