Masitinib

Datasheet MSDS
Catalog Number
SBCR10070
Product Name
Masitinib
CAS Number
790299-79-5
Synonyms
AB1010
Molecular Formula
C28H30N6OS
Molecular Weight
498.64
Purity
100.00%
Solubility
DMSO: 93 mg/mL (186.5 mM) Ethanol: 4 mg/mL (8.02 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Masitinib (AB1010) is a novel Kit and PDGFRα/β inhibitor with IC50 of 200 nM and 540 nM/800 nM, respectively, but has a weak inhibitory effect on ABL and c-Fms. Phase 3。
Target
Abl1, c-Fms, Hck, Kit, Lyn B, PDGFRα, PDGFRβ, Src
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