Obatoclax mesylate

Catalog Number
SBCL10832
Product Name
Obatoclax mesylate
CAS Number
803712-79-0
Synonyms
GX15-070 , Obatoclax , Obatoclax GX15-070
Molecular Formula
C20H19N3O·CH4O3S
Molecular Weight
413.49
Purity
99.67%
Solubility
DMSO: 77 mg/mL (186.2 mM) Ethanol: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Obatoclax is a Bcl-2 antagonist (Ki: 0.22 μM) and can induce apoptosis with up-regulation of Bim, induced cytochrome c release, and activation of caspase-3.
Target
Bcl-2
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