Palbociclib hydrochloride

Datasheet MSDS
Catalog Number
SCDK11873
Product Name
Palbociclib hydrochloride
CAS Number
827022-32-2
Synonyms
PD 0332991 hydrochloride , Palbociclib (PD-0332991) HCl , PD 0332991 hydrochloride , Palbociclib (PD-0332991) HCl
Molecular Formula
C24H29N7O2·HCl
Molecular Weight
483.99
Purity
99.79%
Solubility
DMSO: 5 mg/mL (10.33 mM) H20: 80mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Palbociclib (PD-0332991) is a selective inhibitor of CDK4/6 (IC50s: 11/16 nM). It exhibits no inhibition against a panel of 36 additional protein kinases.
Target
CDK2/CyclinA, CDK2/CyclinE2, CDK4/CyclinD1, CDK4/CyclinD3, CDK6/CyclinD2
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