RO4929097

Datasheet MSDS
Catalog Number
SBET24967
Product Name
RO4929097
CAS Number
847925-91-1
Synonyms
RG-4733 , RG-4733
Molecular Formula
C22H20F5N3O3
Molecular Weight
469.4
Purity
99.51%
Solubility
DMSO: 86 mg/mL (183.2 mM) Ethanol: 13 mg/mL (27.7 mM) Water: Insoluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
RO4929097, a γ secretase inhibitor (IC50: 4 nM), inhibits cellular processing of Aβ40 and Notch (EC50: 14/5 nM).
Target
Aβ40, γ secretase, γ secretase(ICN), Notch
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