Catalog Number
SBCR10077
Product Name
BAW2881
CAS Number
861875-60-7
Synonyms
NVP-BAW2881
Molecular Formula
C22H15F3N4O2
Molecular Weight
424.38
Purity
99.97%
Solubility
DMSO: 78 mg/mL (183.8 mM) Ethanol: 16 mg/mL (37.7 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
BAW2881 (NVP-BAW2881) is a novel VEGFR tyrosine kinase inhibitor. It can effectively inhibit VEGFR1-3 at a concentration of 1.0-4.3 nM. At concentrations of 45-72 nM, PDGFRβ, c-Kit and RET (c-RET) are inhibited.
Target
B-Raf (V599E), c-Abl, C-Raf-1, hVEGFR2
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