C 021 dihydrochloride

Datasheet MSDS
Catalog Number
SCCR17365
Product Name
C 021 dihydrochloride
CAS Number
864289-85-0
Synonyms
4-Quinazolinamine, 2-[1,4'-bipiperidin]-1'-yl-N-cycloheptyl-6,7-dimethoxy-
Molecular Formula
C27H41N5O2
Molecular Weight
467.65
Purity
99.74%
Solubility
DMSO: Soluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
C 021 dihydrochloride is a potent CCR4 antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in humans and mice with IC50s of 140 nM and 39 nM, respectively. It effectively prevents human CCL22-derived [35S]GTPγS from binding to the receptor (IC50: 18 nM).
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