IN-1130

Datasheet MSDS
Catalog Number
SALK10037
Product Name
IN-1130
CAS Number
868612-83-3
Molecular Formula
C25H20N6O
Molecular Weight
420.47
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
IN-1130 is a highly selective inhibitor of transforming growth factor-β type I receptor kinase (ALK5) (IC50: 5.3 nM for ALK5-mediated Smad3 phosphorylation). IN-1130 inhibits ALK5 phosphorylation of casein (IC50: 36 nM) and p38α mitogen-activated protein kinase (IC50: 4.3 μM).
Target
ALK5
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