E 2012

Datasheet MSDS
Catalog Number
SGAM25634
Product Name
E 2012
CAS Number
870843-42-8
Molecular Formula
C25H26FN3O2
Molecular Weight
419.49
Purity
99.83%
Solubility
DMSO: 50 mg/mL (119.19 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
E2012 is a γ-secretase modulator (GSM). E2012 inhibits 3β-hydroxysterol Δ24-reductase (DHCR24) at the final step in the cholesterol biosynthesis. E 2012 aims at Alzheimer's disease by reduction of amyloid β-42, and induces cataract following repeated doses in the rat.
Target
Others
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