TAK285

Datasheet MSDS
Catalog Number
SEGF10200
Product Name
TAK285
CAS Number
871026-44-7
Synonyms
TAK-285, TAK 285
Molecular Formula
C26H25ClF3N5O3
Molecular Weight
547.96
Purity
98.0%
Solubility
DMSO: 102 mg/mL (186.1 mM) Ethanol: 50 mg/mL (91.2 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
TAK-285 is a novel, HER2 and EGFR (HER1) dual inhibitors, IC50 are 17nM and 23nM, acting on HER1/2 is more selective than Chemicalbook acting on HER4 more than 10 times, and the effect on MEK1/5, c-Met, AuroraB, Lck, CSK and so on is slightly weaker. Phase1。
Target
Aurora B, EGFR/HER1, HER2, HER4, MEK1
Inquiry

new products