Vismodegib

Datasheet MSDS
Catalog Number
SHED16591
Product Name
Vismodegib
CAS Number
879085-55-9
Synonyms
GDC-0449 , Erivedge , RG 3616
Molecular Formula
C19H14Cl2N2O3S
Molecular Weight
421.3
Purity
99.99%
Solubility
DMSO: 78 mg/mL (185.1 mM) Ethanol: Insoluble Water: Insoluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Vismodegib is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).
Target
Hedgehog, P-gp, ABCG2
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