Catalog Number
SBCR10103
Product Name
AT9283
CAS Number
896466-04-9
Synonyms
J-504568
Molecular Formula
C19H23N7O2
Molecular Weight
381.43
Purity
99.98%
Solubility
DMSO: 71 mg/mL (186.1 mM) Ethanol: 22 mg/mL (57.7 mM) Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
AT9283 is a potent JAK2/3 inhibitor with an IC50 of 1.2 nM/1.1 nM; Also valid for Aurora A/B, Abl (T315I). Phase 2。
Target
Abl1 (T315I), Aurora A, Aurora B, JAK2, JAK3
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