Catalog Number
SFLT10445
Product Name
VX-11e
CAS Number
896720-20-0
Synonyms
VTX-11e, Vertex-11e, TCS ERK 11e
Molecular Formula
C24H20Cl2FN5O2
Molecular Weight
500.35
Purity
99.67%
Solubility
DMSO: 50 mg/mL (100 mM) Ethanol: 12.5 mg/mL (25 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
VX-11e (VTX-11e, Vertex-11e) is a potent, selective, and oral bioavailable ERK2 inhibitor with Ki <2 nM, which is 200 times more selective than kinase acting on other tests.
Target
Aurora A, CDK2, ERK2, FLT3, GSK-3
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