ALK5 Inhibitor IV

Datasheet MSDS
Catalog Number
SALK10057
Product Name
ALK5 Inhibitor IV
CAS Number
909910-43-6
Synonyms
A 83-01
Molecular Formula
C25H19N5S
Molecular Weight
421.52
Purity
98.76%
Solubility
DMSO: >10 mM ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
A-83-01 is an effective inhibitor of TGF-βtypeIreceptor(ALK5-TD), and its IC50 value is 12nM. A - 83-01 inhibition by activin/nodaltChemicalbookypeIreceptor ALK4 - (TD) and nodaltypeIreceptor (ALK7 - TD) induced transcription, corresponding to the IC50 alue concentration of 45 nM and 7.5 nM, respectively. Available now.
Target
ALK4, ALK5, ALK7
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