Dactolisib

Datasheet MSDS
Catalog Number
SATM14111
Product Name
Dactolisib
CAS Number
915019-65-7
Synonyms
NVP-BEZ235 , BEZ235
Molecular Formula
C30H23N5O
Molecular Weight
469.54
Purity
99.85%
Solubility
DMSO: 5.2 mg/mL (11.07 mM), Need ultrasonic and warming H2O: < 0.1 mg/mL (insoluble) ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Dactolisib is an orally bioavailable inhibitor of PI3K and mTOR (IC50s: 4 nM/5 nM/7 nM/75 nM, and 20.7 nM for p110α/p110γ/p110δ/p110β and mTOR).
Target
ATR, mTOR (p70S6K), p110α, p110γ, p110δ, p110β
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