Vemurafenib

Datasheet MSDS
Catalog Number
SMAP19260
Product Name
Vemurafenib
CAS Number
918504-65-1
Synonyms
PLX4032 , RO5185426 , RG7204
Molecular Formula
C23H18ClF2N3O3S
Molecular Weight
489.92
Purity
99.65%
Solubility
DMSO: 90 mg/mL (183.7 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Vemurafenib (PLX4032) is a novel and potent B-Raf (V600E) inhibitor (IC50: 31 nM).
Target
ACK1, BLK, B-Raf, B-Raf (V600E), BRK, C-Raf, CSK, FGR, FRK (PTK5), Lck, Lyn B, MAP4K5 (KHS1), MNK2, NEK11, Src, SRMS, WNK3, Yes1, c-Raf-1
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