Navitoclax

Datasheet MSDS
Catalog Number
SBCL10831
Product Name
Navitoclax
CAS Number
923564-51-6
Synonyms
ABT-263
Molecular Formula
C47H55ClF3N5O6S3
Molecular Weight
974.61
Purity
100.00%
Solubility
DMSO: 93 mg/mL (95.4 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Navitoclax (ABT-263) is a potent, orally bioavailable Bcl-2 family protein inhibitor that avidly binds Bcl-2, Bcl-xL, and Bcl-W (Ki < 1 nM for all three proteins).
Target
Bcl-2, Bcl-w, Bcl-xL
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