ENMD2076

Datasheet MSDS
Catalog Number
SFLT10467
Product Name
ENMD2076
CAS Number
934353-76-1
Synonyms
ENMD 2076, ENMD-2076
Molecular Formula
C21H25N7
Molecular Weight
375.47
Purity
98.00%
Solubility
DMSO: 97 mg/mL (258.3 mM) Water: 1 mg/mL (2.66 mM) Ethanol: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
ENMD-2076 selectively acts on AuroraA and VEGFR (Flt3), IC50 is 14nM and 1.86nM, respectively, acting on AuroraA is 25 times more selective than Acting Chemicalbook on AuroraB, and has a slightly weaker effect on VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFRα. Phase2。
Target
Aurora A, FLT3, RET, Src, VEGFR3/FLT4
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