Catalog Number
SPKC13291
Product Name
GSK690693
CAS Number
937174-76-0
Molecular Formula
C21H27N7O3
Molecular Weight
425.48
Purity
100.00%
Solubility
DMSO: 21.3 mg/mL(50 mM) DMF: soluble ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
GSK690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.
Target
Akt1, Akt3, PKCη, PKCθ, PrkX
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