AMG900

Datasheet MSDS
Catalog Number
SAUR11861
Product Name
AMG900
CAS Number
945595-80-2
Synonyms
AMG 900 , AMG-900 , AMG-900 AMG 900
Molecular Formula
C28H21N7OS
Molecular Weight
503.58
Purity
98.40%
Solubility
DMSO: 93 mg/mL (184.7 mM) Ethanol: <1 mg/mL Water: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
AMG 900 is a potent and highly selective pan-Aurora kinases inhibitor for Aurora A/B/C with IC50 of 5 nM/4 nM /1 nM. It is >10-fold selective for Aurora kinases than p38α, Tyk2, JNK2, Met and Tie2. Phase 1.
Target
Aurora A, Aurora B, Aurora C, p38α, Tyk2
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