Gemcitabine

Datasheet MSDS
Catalog Number
SAUT11567
Product Name
Gemcitabine
CAS Number
95058-81-4
Synonyms
LY188011 , NSC 613327
Molecular Formula
C9H11F2N3O4
Molecular Weight
263.2
Purity
99.67%
Solubility
DMSO: 15 mg/mL (56.99 mM) Ethanol: <1 mg/mL ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
Gemcitabine is a DNA synthesis inhibitor that can inhibit the growth of MIAPaCa2, BxPC3 and Capan2 cells (IC50s: 40/18/12 nM). It can also induce autophagy.
Target
Autophagy, Thymidylate synthase, UMP-CMP kinase
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