CM-579 trihydrochloride

Datasheet MSDS
Catalog Number
SDNA12578
Product Name
CM-579 trihydrochloride
Synonyms
CM-579 trihydrochloride (1846570-40-8 free base)
Molecular Formula
C29H43Cl3N4O3
Molecular Weight
602.04
Solubility
DMSO: 125 mg/mL (207.63 mM), Need ultrasonic MEthanol: 75 mg/mL (124.58 mM), Need ultrasonic H2O: 37.5 mg/mL (62.29 mM), Need ultrasonic ( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage
Powder: -20°C for 3 years In solvent: -80°C for 6 months
Description
CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide range of cancer cells.
Target
DNA Methyltransferase, DNMT1, DNMT3A, DNMT3B, G9a
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